Biotechnology: Antibodies & their role in Therapeutics
Learn about Antibodies: Their Structure, Types, Functions and Role in Therapeutics & Diagnostics | Immunology | Biology
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5.5 hours
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May 2023
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$84.99
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What you will learn
1. Structure of antibodies
2. Types of light and heavy chains of antibodies
3. Complementarity Determining Regions (CDRs) & how they bind to antigen
4. Immunoglobulin domains
5. Framework region
6. Classes of antibodies: IgG, IgM, IgA, IgE, IgD & their biological activities
7. What is opsonization, ADCC and complement system
8. Pathways of complement activation
9. Regulation of complement system
10. Organization and expression of immunoglobulin genes
11. Mechanism of VJ and VDJ recombination
12. Generation of antibody diversity
13. Somatic Hypermutation
14. Class switching mechanism & factors governing it
15. Expression of membrane bound & secreted form of immunoglobulins
16. B cell receptors (BCRs)
17. Simultaneous expression of IgM and IgD on B cells
18. Regulation of Ig gene transcription
19. Differences between polyclonal and monoclonal antibodies
20. Hybridoma Technology
21. Therapeutic monoclonal antibodies
22. Antibody engineering: Chimeric monoclonal antibodies
23. Humanized monoclonal antibodies
24. Fully human monoclonal antibodies
25. Immunogenicity of engineered monoclonal antibodies
26. Immunotoxins
27. Bispecific antibodies
28. Abzymes
29. Convalescent plasma therapy
30. How is plasma therapy being used for the treatment of COVID-19 disease
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3249112
udemy ID
6/18/2020
course created date
8/23/2020
course indexed date
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